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- Title
Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): randomised double-blind trial.
- Authors
Courtney, C; Farrell, D; Gray, R; Hills, R; Lynch, L; Sellwood, E; Edwards, S; Hardyman, W; Raftery, J; Crome, P; Lendon, C; Shaw, H; Bentham, P; AD2000 Collaborative Group
- Abstract
Cholinesterase inhibitors produce small improvements in cognitive and global assessments in Alzheimer's disease. We aimed to determine whether donepezil produces worthwhile improvements in disability, dependency, behavioural and psychological symptoms, carers' psychological wellbeing, or delay in institutionalisation. If so, which patients benefit, from what dose, and for how long?
- Publication
Lancet (London, England), 2004, Vol 363, Issue 9427, p2105
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(04)16499-4