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- Title
Combination antifungal therapies for HIV-associated cryptococcal meningitis: a randomised trial.
- Authors
Brouwer, Annemarie E; Rajanuwong, Adul; Chierakul, Wirongrong; Griffin, George E; Larsen, Robert A; White, Nicholas J; Harrison, Thomas S
- Abstract
It frequently takes more than 2 weeks for drug treatments for cryptococcal meningitis to sterilise cerebrospinal fluid (CSF). In-vitro and animal studies lend support to the use of combinations of amphotericin B, flucytosine, and fluconazole for treatment of cryptococcosis. We compared the fungicidal activity of combinations of these drugs for initial treatment of patients with cryptococcal meningitis.
- Publication
Lancet (London, England), 2004, Vol 363, Issue 9423, p1764
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(04)16301-0