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- Title
Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions.
- Authors
Collins, Rory; Armitage, Jane; Parish, Sarah; Sleight, Peter; Peto, Richard; Heart Protection Study Collaborative Group
- Abstract
Lower blood cholesterol concentrations have consistently been found to be strongly associated with lower risks of coronary disease but not with lower risks of stroke. Despite this observation, previous randomised trials had indicated that cholesterol-lowering statin therapy reduces the risk of stroke, but large-scale prospective confirmation has been needed.
- Publication
Lancet (London, England), 2004, Vol 363, Issue 9411, p757
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(04)15690-0