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- Title
Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial.
- Authors
Christ-Crain, Mirjam; Jaccard-Stolz, Daiana; Bingisser, Roland; Gencay, Mikael M; Huber, Peter R; Tamm, Michael; Müller, Beat
- Abstract
Lower respiratory tract infections are often treated with antibiotics without evidence of clinically relevant bacterial disease. Serum calcitonin precursor concentrations, including procalcitonin, are raised in bacterial infections. We aimed to assess a procalcitonin-based therapeutic strategy to reduce antibiotic use in lower respiratory tract infections with a new rapid and sensitive assay.
- Publication
Lancet (London, England), 2004, Vol 363, Issue 9409, p600
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(04)15591-8