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- Title
Prediabetes in obese youth: a syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning.
- Authors
Weiss, Ram; Dufour, Sylvie; Taksali, Sara E; Tamborlane, William V; Petersen, Kitt F; Bonadonna, Riccardo C; Boselli, Linda; Barbetta, Gina; Allen, Karin; Rife, Francis; Savoye, Mary; Dziura, James; Sherwin, Robert; Shulman, Gerald I; Caprio, Sonia
- Abstract
Impaired glucose tolerance is common among obese adolescents, but the changes in insulin sensitivity and secretion that lead to this prediabetic state are unknown. We investigated whether altered partitioning of myocellular and abdominal fat relates to abnormalities in glucose homoeostasis in obese adolescents with prediabetes.
- Publication
Lancet (London, England), 2003, Vol 362, Issue 9388, p951
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(03)14364-4