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- Title
Efficacy and safety of seven-valent conjugate pneumococcal vaccine in American Indian children: group randomised trial.
- Authors
O'Brien, Katherine L; Moulton, Lawrence H; Reid, Raymond; Weatherholtz, Robert; Oski, Jane; Brown, Laura; Kumar, Gaurav; Parkinson, Alan; Hu, Diana; Hackell, Jill; Chang, Ih; Kohberger, Robert; Siber, George; Santosham, Mathuram
- Abstract
Streptococcus pneumoniae is the main cause of invasive bacterial disease in children aged younger than 2 years. Navajo and White Mountain Apache children have some of the highest rates of invasive pneumococcal disease documented in the world. We aimed to assess the safety and efficacy of a seven-valent polysaccharide protein conjugate pneumococcal vaccine (PnCRM7) against such disease.
- Publication
Lancet (London, England), 2003, Vol 362, Issue 9381, p355
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(03)14022-6