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- Title
Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency.
- Authors
Chan, C L H; Facer, P; Davis, J B; Smith, G D; Egerton, J; Bountra, C; Williams, N S; Anand, P
- Abstract
Faecal urgency and incontinence with rectal hypersensitivity is a distressing, unexplained disorder that is inadequately treated. We aimed to determine whether expression of the heat and capsaicin receptor vanilloid receptor 1 (TRPV1 or VR1) was changed in rectal sensory fibres, and to correlate nerve fibre density with sensory abnormalities.
- Publication
Lancet (London, England), 2003, Vol 361, Issue 9355, p385
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/s0140-6736(03)12392-6