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- Title
Effect of T-cell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats: a randomised controlled trial.
- Authors
Oldfield, W L G; Larché, M; Kay, A B
- Abstract
Some patients with asthma who are allergic to cats and are injected intradermally with short, overlapping, T-cell peptides derived from Fel d 1 develop late asthmatic reactions to the peptides, which are associated with a reduction in late-phase skin reactions induced by whole allergens and bronchial hyporesponsiveness to the peptides on the second injection. We aimed to ascertain the effect of multiple injections on the magnitude of the early and late phase skin reactions to intact allergens.
- Publication
Lancet (London, England), 2002, Vol 360, Issue 9326, p47
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/s0140-6736(02)09332-7