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- Title
Multidrug-resistance protein 1 in focal cortical dysplasia.
- Authors
Sisodiya, S M; Lin, W R; Squier, M V; Thom, M
- Abstract
Drug resistance in epilepsy is poorly understood. We used routine immunohistochemistry to assess overexpression of a multidrug-resistance protein in dysplastic neurons, glia, and around vessels in surgically resected epileptogenic human brain tissue. We showed non-tumoral overexpression of this multidrug-resistance protein, which might contribute to drug resistance in epilepsy caused by focal cortical dysplasia.
- Publication
Lancet (London, England), 2001, Vol 357, Issue 9249, p42
- ISSN
0140-6736
- Publication type
Research
- DOI
10.1016/s0140-6736(00)03573-x