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Title
Statins and the risk of dementia.
Authors
Jick, H; Zornberg, G L; Jick, S S; Seshadri, S; Drachman, D A
Abstract
Dementia affects an estimated 10% of the population older than 65 years. Because vascular and lipid-related mechanisms are thought to have a role in the pathogenesis of Alzheimer's disease and vascular dementia, we did an epidemiological study of the potential effect of HMGCoA (3 hydroxy-3methylglutaryl-coenzyme A) reductase inhibitors (statins) and other lipid-lowering agents on dementia.