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- Title
The uncertainty principle and industry-sponsored research.
- Authors
Djulbegovic, B; Lacevic, M; Cantor, A; Fields, K K; Bennett, C L; Adams, J R; Kuderer, N M; Lyman, G H
- Abstract
Reporting of pharmaceutical-industry-sponsored randomised clinical trials often result in biased findings, either due to selective reporting of studies with non-equivalent arms or publication of low-quality papers, wherein unfavourable results are incompletely described. A randomised trial should be conducted only if there is substantial uncertainty about the relative value of one treatment versus another. Studies in which intervention and control are thought to be non-equivalent violates the uncertainty principle.
- Publication
Lancet (London, England), 2000, Vol 356, Issue 9230, p635
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(00)02605-2