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- Title
Effect of local radiotherapy for bone pain on urinary markers of osteoclast activity.
- Authors
Hoskin, P J; Stratford, M R; Folkes, L K; Regan, J; Yarnold, J R
- Abstract
Urinary markers of bone resorption, pyridinoline and deoxypyridinoline were measured before and at 4 weeks after radiotherapy for metastatic bone pain. An association was shown between relief of metastatic skeletal pain by radiotherapy and low marker concentrations before and after treatment, lending support to the hypothesis that relief of metastatic bone pain by radiotherapy relates to an effect on bone, rather than tumour physiology.
- Publication
Lancet (London, England), 2000, Vol 355, Issue 9213, p1428
- ISSN
0140-6736
- Publication type
Commentary
- DOI
10.1016/s0140-6736(00)02144-9