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Title
Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?
Authors
Hausenloy, Derek J; Maddock, Helen L; Baxter, Gary F; Yellon, Derek M
Abstract
We propose that ischemic preconditioning (IPC) and mitochondrial K(ATP) channel activation protect the myocardium by inhibiting mitochondrial permeability transition pore (MPTP) opening at reperfusion.