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Title
Effects of homocysteine on murine splenic B lymphocyte proliferation and its signal transduction mechanism.
Authors
Zhang, Q; Zeng, X; Guo, J; Wang, X
Abstract
Elevated plasma homocysteine (Hcy) levels have been defined as an increased risk of atherosclerosis. However, the mechanisms that Hcy induces the development of atherosclerosis are not fully understood. Therefore, effect of Hcy on B lymphocyte proliferation and its cellular mechanism were examined in normal and hyperhomocysteinemia ApoE-knockout mice.