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- Title
Seronegative conversion after incomplete benznidazole treatment in chronic Chagas disease.
- Authors
Alvarez, M G; Vigliano, C; Lococo, B; Petti, M; Bertocchi, G; Viotti, R
- Abstract
In 12-18% of adult patients, treatment with benznidazole for chronic Chagas disease has to be discontinued because of side-effects. We identified and analysed a cohort of 81 adult patients with three positive tests for Trypanosoma cruzi infection and serological monitoring following incomplete treatment with benznidazole for a median of 10 days. Twenty percent of these patients (16/81) met the criteria of cure, showing that the optimal schedule of benznidazole administration remains to be determined.
- Publication
Transactions of the Royal Society of Tropical Medicine and Hygiene, 2012, Vol 106, Issue 10, p636
- ISSN
1878-3503
- Publication type
Journal Article
- DOI
10.1016/j.trstmh.2012.07.010