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- Title
Significant changes in the alloantibody after lung transplantation in the cyclosporine treated rat model.
- Authors
Yamane, Masaomi; Sano, Yoshifumi; Shimizu, Nobuyoshi
- Abstract
The diagnosis of acute rejection after organ transplantation is often complicated by other possibilities, such as infection. Despite many attempts to identify rejection episodes after transplantation, only the detection of the humoral anti-human leukocyte antigen antibody has been effective in measuring alloimmunization, especially detected with flow cytometry cross-match (FCXM). As an initial step towards gaining a better understanding of the correlation between humoral responses and graft rejection in an immunosuppressant recipient, we investigated responses of alloantibodies (allo-Abs) after lung transplantation (LTx) in a rat model treated with adequate or inadequate cyclosporine A (CsA) therapy.
- Publication
Transplant immunology, 2004, Vol 12, Issue 2, p143
- ISSN
0966-3274
- Publication type
Journal Article
- DOI
10.1016/j.trim.2003.09.002