We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Epithelial mesenchymal transition in colorectal cancer: Seminal role in promoting disease progression and resistance to neoadjuvant therapy.
- Authors
Bhangu, Aneel; Wood, Gemma; Mirnezami, Alex; Darzi, Ara; Tekkis, Paris; Goldin, Robert
- Abstract
Epithelial mesenchymal transition (EMT) may be physiological as part of embryological development, or pathological as part of cancer development. It is one of the key initiating events in the metastatic cascade. EMT has profound effects on tumour cell invasiveness, proliferation and motility. In the present article we aimed to review the potential role of EMT as a process to explain colorectal cancer progression and resistance to neoadjuvant therapy.
- Publication
Surgical oncology, 2012, Vol 21, Issue 4, p316
- ISSN
1879-3320
- Publication type
Journal Article
- DOI
10.1016/j.suronc.2012.08.003