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- Title
Naloxone fails to antagonize initial hypoalgesic effect of a manual therapy treatment for lateral epicondylalgia.
- Authors
Paungmali, Aatit; O'Leary, Shaun; Souvlis, Tina; Vicenzino, Bill
- Abstract
Recent research has shown that Mulligan's Mobilization With Movement treatment technique for the elbow (MWM), a peripheral joint mobilization technique, produces a substantial and immediate pain relief in chronic lateral epicondylalgia (48% increase in pain-free grip strength).([1]) This hypoalgesic effect is far greater than that previously reported with spinal manual therapy treatments, prompting speculation that peripheral manual therapy treatments may differ in mechanism of action to spinal manual therapy techniques. Naloxone antagonism and tolerance studies, which employ widely accepted tests for the identification of endogenous opioid-mediated pain control mechanisms, have shown that spinal manual therapy-induced hypoalgesia does not involve an opioid mechanism.
- Publication
Journal of manipulative and physiological therapeutics, 2004, Vol 27, Issue 3, p180
- ISSN
0161-4754
- Publication type
Journal Article
- DOI
10.1016/j.jmpt.2003.12.022