Works matching AU Singleton, Andrew

Results: 293

Reply to: 'Letter to the Editor on "Sex Differences in Parkinson's Disease Phenotype and Caregiving Disparities"'.

Published in:

2021

By:

Antar, Tarek;
Iwaki, Hirotaka;
Singleton, Andrew;
B Singleton, Andrew

Publication type:

Letter

Structural genomic variation in ischemic stroke.

Published in:

Neurogenetics, 2008, v. 9, n. 2, p. 101, doi. 10.1007/s10048-008-0119-3

By:

Matarin, Mar;
Simon-Sanchez, Javier;
Fung, Hon-Chung;
Scholz, Sonja;
Gibbs, J.;
Hernandez, Dena;
Crews, Cynthia;
Britton, Angela;
Wavrant De Vrieze, Fabienne;
Brott, Thomas;
Brown, Robert;
Worrall, Bradford;
Silliman, Scott;
Case, L.;
Hardy, John;
Rich, Stephen;
Meschia, James;
Singleton, Andrew

Publication type:

Article

Use of support vector machines for disease risk prediction in genome-wide association studies: Concerns and opportunities.

Published in:

Human Mutation, 2012, v. 33, n. 12, p. 1708, doi. 10.1002/humu.22161

By:

Mittag, Florian;
Büchel, Finja;
Saad, Mohamad;
Jahn, Andreas;
Schulte, Claudia;
Bochdanovits, Zoltan;
Simón-Sánchez, Javier;
Nalls, Mike A.;
Keller, Margaux;
Hernandez, Dena G.;
Gibbs, J. Raphael;
Lesage, Suzanne;
Brice, Alexis;
Heutink, Peter;
Martinez, Maria;
Wood, Nicholas W;
Hardy, John;
Singleton, Andrew B.;
Zell, Andreas;
Gasser, Thomas

Publication type:

Article

A thorough assessment of benign genetic variability in GRN and MAPT.

Published in:

Human Mutation, 2010, v. 31, n. 2, p. E1126, doi. 10.1002/humu.21152

By:

Guerreiro, Rita J.;
Washecka, Nicole;
Hardy, John;
Singleton, Andrew

Publication type:

Article

Comprehensive analysis of LRRK2 in publicly available Parkinson's disease cases and neurologically normal controls.

Published in:

Human Mutation, 2008, v. 29, n. 4, p. 485, doi. 10.1002/humu.20668

By:

Paisán-Ruíz, Coro;
Nath, Priti;
Washecka, Nicole;
Gibbs, J. Raphael;
Singleton, Andrew B.

Publication type:

Article

Genomewide SNP assay reveals mutations underlying Parkinson disease.

Published in:

Human Mutation, 2008, v. 29, n. 2, p. 315, doi. 10.1002/humu.20626

By:

Simon-Sanchez, Javier;
Scholz, Sonja;
del Mar Matarin, Maria;
Fung, Hon-Chung;
Hernandez, Dena;
Gibbs, J Raphael;
Britton, Angela;
Hardy, John;
Singleton, Andrew

Publication type:

Article

An evaluation of an educational group for general practitioner continuing education and development.

Published in:

Medical Teacher, 1998, v. 20, n. 6, p. 572, doi. 10.1080/01421599880319

By:

Smith, Frank;
Singleton, Andrew;
Teague, Peta-Ann;
Ross-Harper, Rachel;
Wilke, Gerhard;
Hilton, Sean

Publication type:

Article

SORL1 mutation in a Greek family with Parkinson's disease and dementia.

Published in:

Annals of Clinical & Translational Neurology, 2021, v. 8, n. 10, p. 1961, doi. 10.1002/acn3.51433

By:

Xiromerisiou, Georgia;
Bourinaris, Thomas;
Houlden, Henry;
Lewis, Patrick A.;
Senkevich, Konstantin;
Hammer, Monia;
Federoff, Monica;
Khan, Alaa;
Spanaki, Cleanthe;
Hadjigeorgiou, Georgios M.;
Bonstanjopoulou, Sevasti;
Fidani, Liana;
Ermolaev, Aleksey;
Gan‐Or, Ziv;
Singleton, Andrew;
Vandrovcova, Jana;
Hardy, John

Publication type:

Article

The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort.

Published in:

Annals of Clinical & Translational Neurology, 2018, v. 5, n. 12, p. 1460, doi. 10.1002/acn3.644

By:

Marek, Kenneth;
Chowdhury, Sohini;
Siderowf, Andrew;
Lasch, Shirley;
Coffey, Christopher S.;
Caspell‐Garcia, Chelsea;
Simuni, Tanya;
Jennings, Danna;
Tanner, Caroline M.;
Trojanowski, John Q.;
Shaw, Leslie M.;
Seibyl, John;
Schuff, Norbert;
Singleton, Andrew;
Kieburtz, Karl;
Toga, Arthur W.;
Mollenhauer, Brit;
Galasko, Doug;
Chahine, Lana M.;
Weintraub, Daniel

Publication type:

Article

Genome-wide association study of neocortical Lewy-related pathology.

Published in:

Annals of Clinical & Translational Neurology, 2015, v. 2, n. 9, p. 920, doi. 10.1002/acn3.231

By:

Peuralinna, Terhi;
Myllykangas, Liisa;
Oinas, Minna;
Nalls, Mike A.;
Keage, Hannah A. D.;
Isoviita, Veli‐Matti;
Valori, Miko;
Polvikoski, Tuomo;
Paetau, Anders;
Sulkava, Raimo;
Ince, Paul G.;
Zaccai, Julia;
Brayne, Carol;
Traynor, Bryan J.;
Hardy, John;
Singleton, Andrew B.;
Tienari, Pentti J.

Publication type:

Article

Multiple system atrophy: the application of genetics in understanding etiology.

Published in:

Clinical Autonomic Research, 2015, v. 25, n. 1, p. 19, doi. 10.1007/s10286-014-0267-5

By:

Federoff, Monica;
Schottlaender, Lucia;
Houlden, Henry;
Singleton, Andrew

Publication type:

Article

Primary hyperhidrosis.

Published in:

Clinical Autonomic Research, 2003, v. 13, n. 2, p. 96, doi. 10.1007/s10286-003-0082-x

By:

Kaufmann, Horacio;
Saadia, Daniela;
Polin, Charlene;
Hague, Stephen;
Singleton, Amanda;
Singleton, Andrew

Publication type:

Article

Familiality in simple and complex disease.

Published in:

Clinical Autonomic Research, 2003, v. 13, n. 2, p. 88, doi. 10.1007/s10286-003-0091-9

By:

Singleton, Andrew

Publication type:

Article

Assessment of Genetic Association Between Parkinson Disease and Bipolar Disorder.

Published in:

JAMA Neurology, 2020, v. 77, n. 8, p. 1034, doi. 10.1001/jamaneurol.2020.0248

By:

Bandres-Ciga, Sara;
Blauwendraat, Cornelis;
Singleton, Andrew B.

Publication type:

Article

Common Premutations in the General Population.

Published in:

2019

By:

Hammer, Monia B.;
Singleton, Andrew B.

Publication type:

Opinion

Genome-Wide Analysis of the Heritability of Amyotrophic Lateral Sclerosis.

Published in:

JAMA Neurology, 2014, v. 71, n. 9, p. 1123, doi. 10.1001/jamaneurol.2014.1184

By:

Keller, Margaux F.;
Ferrucci, Luigi;
Singleton, Andrew B.;
Tienari, Pentti J.;
Laaksovirta, Hannu;
Restagno, Gabriella;
Chiò, Adriano;
Traynor, Bryan J.;
Nalls, Michael A.

Publication type:

Article

A 6.4 Mb Duplication of the a-Synuclein Locus Causing Frontotemporal Dementia and Parkinsonism Phenotype-Genotype Correlations.

Published in:

JAMA Neurology, 2014, v. 71, n. 9, p. 1162, doi. 10.1001/jamaneurol.2014.994

By:

Kara, Eleanna;
Kiely, Aoife P.;
Proukakis, Christos;
Giffin, Nicola;
Love, Seth;
Hehir, Jason;
Rantell, Khadija;
Pandraud, Amelie;
Hernandez, Dena G.;
Nacheva, Elizabeth;
Pittman, Alan M.;
Nalls, Mike A.;
Singleton, Andrew B.;
Revesz, Tamas;
Bhatia, Kailash P.;
Quinn, Niall;
Hardy, John;
Holton, Janice L.;
Houlden, Henry

Publication type:

Article

Association of Cerebrospinal Fluid β-Amyloid 1-42, T-tau, P-tau<sub>181</sub>, and α-Synuclein Levels With Clinical Features of Drug-Naive Patients With Early Parkinson Disease.

Published in:

JAMA Neurology, 2013, v. 70, n. 10, p. 1277, doi. 10.1001/jamaneurol.2013.3861

By:

Ju-Hee Kang;
Irwin, David J.;
Chen-Plotkin, Alice S.;
Siderowf, Andrew;
Caspell, Chelsea;
Coffey, Christopher S.;
Waligórska, Teresa;
Taylor, Peggy;
Pan, Sarah;
Frasier, Mark;
Marek, Kenneth;
Kieburtz, Karl;
Jennings, Danna;
Simuni, Tanya;
Tanner, Caroline M.;
Singleton, Andrew;
Toga, Arthur W.;
Chowdhury, Sohini;
Mollenhauer, Brit;
Trojanowski, John Q.

Publication type:

Article

Magnitude of extreme heat waves in present climate and their projection in a warming world.

Published in:

Journal of Geophysical Research. Atmospheres, 2014, v. 119, n. 22, p. 12,500, doi. 10.1002/2014JD022098

By:

Russo, Simone;
Dosio, Alessandro;
Graversen, Rune G.;
Sillmann, Jana;
Carrao, Hugo;
Dunbar, Martha B.;
Singleton, Andrew;
Montagna, Paolo;
Barbola, Paulo;
Vogt, Jürgen V.

Publication type:

Article

Methodological challenges of designing a survey to capture young people's (non-binary) affiliations in relationship to religion, sexuality and gender.

Published in:

International Journal of Social Research Methodology, 2020, v. 23, n. 6, p. 695, doi. 10.1080/13645579.2020.1763692

By:

Rasmussen, Mary Lou;
Graefenstein, Sulamith;
Singleton, Andrew;
Halafoff, Anna;
Bouma, Gary

Publication type:

Article

Genetic variability at the PARK16 locus.

Published in:

European Journal of Human Genetics, 2010, v. 18, n. 12, p. 1356, doi. 10.1038/ejhg.2010.125

By:

Tucci, Arianna;
Nalls, Mike A.;
Houlden, Henry;
Revesz, Tamas;
Singleton, Andrew B.;
Wood, Nicholas W.;
Hardy, John;
Paisán-Ruiz, Coro

Publication type:

Article

Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes.

Published in:

European Journal of Human Genetics, 2001, v. 9, n. 9, p. 659, doi. 10.1038/sj.ejhg.5200698

By:

West, Andrew B;
Zimprich, Alexander;
Lockhart, Paul J;
Farrer, Matthew;
Singleton, Andrew;
Holtom, Benjamin;
Lincoln, Sarah;
Hofer, Anne;
Hill, Lori;
Müller-Myhsok, Bertram;
Wszolek, Zbigniew K;
Hardy, John;
Gasser, Thomas

Publication type:

Article

Genotype-phenotype correlations and expansion of the molecular spectrum of AP4M1-related hereditary spastic paraplegia.

Published in:

2017

By:

Bettencourt, Conceição;
Salpietro, Vincenzo;
Efthymiou, Stephanie;
Chelban, Viorica;
Hughes, Deborah;
Pittman, Alan M.;
Federoff, Monica;
Bourinaris, Thomas;
Spilioti, Martha;
Deretzi, Georgia;
Kalantzakou, Triantafyllia;
Houlden, Henry;
Singleton, Andrew B.;
Xiromerisiou, Georgia

Publication type:

journal article

Erratum: Mutations in TTBK2, encoding a kinase implicated in tau phosphorylation, segregate with spinocerebellar ataxia type 11.

Published in:

2008

By:

Houlden, Henry;
Johnson, Janel;
Gardner-Thorpe, Christopher;
Lashley, Tammaryn;
Hernandez, Dena;
Worth, Paul;
Singleton, Andrew B.;
Hilton, David A.;
Holton, Janice;
Revesz, Tamas;
Davis, Mary B.;
Giunti, Paolo;
Wood, Nicholas W.

Publication type:

Correction Notice

Mutations in TTBK2, encoding a kinase implicated in tau phosphorylation, segregate with spinocerebellar ataxia type 11.

Published in:

Nature Genetics, 2007, v. 39, n. 12, p. 1434, doi. 10.1038/ng.2007.43

By:

Houlden, Henry;
Johnson, Janel;
Gardner-Thorpe, Christopher;
Lashley, Tammaryn;
Hernandez, Dena;
Worth, Paul;
Singleton, Andrew B.;
Hilton, David A.;
Holton, Janice;
Revesz, Tamas;
Davis, Mary B.;
Giunti, Paolo;
Wood, Nicholas W.

Publication type:

Article

A common variation in deiodinase 1 gene DIO1 is associated with the relative levels of free thyroxine and triiodothyronine.

Published in:

2008

By:

Panicker, Vijay;
Cluett, Christie;
Shields, Beverley;
Murray, Anna;
Parnell, Kirstie S;
Perry, John R B;
Weedon, Michael N;
Singleton, Andrew;
Hernandez, Dena;
Evans, Jonathan;
Durant, Claire;
Ferrucci, Luigi;
Melzer, David;
Saravanan, Ponnusamy;
Visser, Theo J;
Ceresini, Graziano;
Hattersley, Andrew T;
Vaidya, Bijay;
Dayan, Colin M;
Frayling, Timothy M

Publication type:

journal article

Cell population-specific expression analysis of human cerebellum.

Published in:

BMC Genomics, 2012, v. 13, n. 1, p. 1, doi. 10.1186/1471-2164-13-610

By:

Kuhn, Alexandre;
Kumar, Azad;
Beilina, Alexandra;
Dillman, Allissa;
Cookson, Mark R.;
Singleton, Andrew B.

Publication type:

Article

Analysis of familial and sporadic restless legs syndrome in age of onset, gender, and severity features.

Published in:

Journal of Neurology, 2004, v. 251, n. 11, p. 1398, doi. 10.1007/s00415-004-0552-7

By:

Hanson, Melissa;
Honour, Melissa;
Singleton, Amanda;
Crawley, Anthony;
Singleton, Andrew;
Hardy, John;
Gwinn-Hardy, Katrina

Publication type:

Article

Leucine rich repeat kinase knockout (LRRK KO) mouse model: Linking pathological hallmarks of inherited and sporadic Parkinson's disease.

Published in:

2018

By:

Roosen, Dorien A.;
Singleton, Andrew B.

Publication type:

journal article

Parkinson disease and clathrin coat dynamics at synapses, why not?

Published in:

2017

By:

Saez‐Atienzar, Sara;
Singleton, Andrew B.;
Saez-Atienzar, Sara

Publication type:

journal article

No clear support for a role for vitamin D in Parkinson's disease: A Mendelian randomization study.

Published in:

2017

By:

Larsson, Susanna C.;
Singleton, Andrew B.;
Nalls, Mike A.;
Richards, J. Brent;
International Parkinson's Disease Genomics Consortium (IPDGC)

Publication type:

journal article

Make dopamine neurons great again: An exciting new therapeutic option in parkinson's disease.

Published in:

2017

By:

Bonet‐Ponce, Luis;
Singleton, Andrew B.;
Bonet-Ponce, Luis

Publication type:

journal article

Arguing against the proposed definition changes of PD.

Published in:

2016

By:

Boeve, Bradley F.;
Dickson, Dennis W.;
Duda, John E.;
Ferman, Tanis J.;
Galasko, Douglas R.;
Galvin, James E.;
Goldman, Jennifer G.;
Growdon, John H.;
Hurtig, Howard I.;
Kaufer, Daniel I.;
Kantarci, Kejal;
Leverenz, James B.;
Lippa, Carol F.;
Lopez, Oscar L.;
McKeith, Ian G.;
Singleton, Andrew B.;
Taylor, Angela;
Tsuang, Debby;
Weintraub, Daniel;
Zabetian, Cyrus P.

Publication type:

journal article

Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI).

Published in:

2016

By:

Nalls, Mike A.;
Keller, Margaux F.;
Hernandez, Dena G.;
Chen, Lan;
Stone, David J.;
Singleton, Andrew B.;
Parkinson's Progression Marker Initiative (PPMI) investigators

Publication type:

journal article

Genetic risk and age in Parkinson's disease: Continuum not stratum.

Published in:

Movement Disorders, 2015, v. 30, n. 6, p. 850, doi. 10.1002/mds.26192

By:

Nalls, Mike A.;
Escott‐Price, Valentina;
Williams, Nigel M.;
Lubbe, Steven;
Keller, Margaux F.;
Morris, Huw R.;
Singleton, Andrew B.

Publication type:

Article

X-linked Parkinson's disease.

Published in:

2015

By:

Singleton, Andrew

Publication type:

Editorial

A 7.5-Mb duplication at chromosome 11q21-11q22.3 is associated with a novel spastic ataxia syndrome.

Published in:

Movement Disorders, 2015, v. 30, n. 2, p. 262, doi. 10.1002/mds.26059

By:

Johnson, Janel O.;
Stevanin, Giovanni;
van de Leemput, Joyce;
Hernandez, Dena G.;
Arepalli, Sampath;
Forlani, Sylvie;
Zonozi, Reza;
Gibbs, J. Raphael;
Brice, Alexis;
Durr, Alexandra;
Singleton, Andrew B.

Publication type:

Article

No association between polymorphisms in the glutamate transporter SLC1A2 and Parkinson's disease.

Published in:

Movement Disorders, 2013, v. 28, n. 9, p. 1305, doi. 10.1002/mds.25330

By:

Appenzeller, Silke;
Schulte, Claudia;
Thier, Sandra;
Hopfner, Franziska;
Pendziwiat, Manuela;
Papengut, Frank;
Klein, Christine;
Hagenah, Johann;
Kasten, Meike;
Srulijes, Karin;
Berg, Daniela;
Gasser, Thomas;
Singleton, Andrew;
Deuschl, Günther;
Kuhlenbäumer, Gregor

Publication type:

Article

The genetics of Parkinson's disease: Progress and therapeutic implications.

Published in:

Movement Disorders, 2013, v. 28, n. 1, p. 14, doi. 10.1002/mds.25249

By:

Singleton, Andrew B.;
Farrer, Matthew J.;
Bonifati, Vincenzo

Publication type:

Article

Rapid genetic diagnosis in single-gene movement disorders.

Published in:

Movement Disorders, 2012, v. 27, n. 4, p. 467, doi. 10.1002/mds.24896

By:

Singleton, Andrew B.

Publication type:

Article

Parkinson's disease and α-synuclein expression.

Published in:

2011

By:

Devine MJ;
Gwinn K;
Singleton A;
Hardy J;
Devine, Michael J;
Gwinn, Katrina;
Singleton, Andrew;
Hardy, John

Publication type:

journal article

Parkinson's disease and α-synuclein expression.

Published in:

Movement Disorders, 2011, v. 26, n. 12, p. 2160, doi. 10.1002/mds.23948

By:

Devine, Michael J.;
Gwinn, Katrina;
Singleton, Andrew;
Hardy, John

Publication type:

Article

Clinical features, with video documentation, of the original familial lewy body parkinsonism caused by α-synuclein triplication (Iowa kindred).

Published in:

Movement Disorders, 2011, v. 26, n. 11, p. 2134, doi. 10.1002/mds.23776

By:

Gwinn, Katrina;
Devine, Michael J.;
Jin, Lee-Way;
Johnson, Janel;
Bird, Thomas;
Muenter, Manfred;
Waters, Cheryl;
Adler, Charles H.;
Caselli, Richard;
Houlden, Henry;
Lopez, Grisel;
Singleton, Amanda;
Hardy, John;
Singleton, Andrew

Publication type:

Article

: A new player in Parkinson's disease.

Published in:

2011

By:

Singleton, Andrew B.

Publication type:

journal article

One beginning, many ends: Mutations in one gene causing varied clinical entities.

Published in:

Movement Disorders, 2011, v. 26, n. 3, p. 379, doi. 10.1002/mds.23666

By:

Singleton, Andrew B.

Publication type:

Article

Early-onset L-dopa-responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations.

Published in:

Movement Disorders, 2010, v. 25, n. 12, p. 1791, doi. 10.1002/mds.23221

By:

Paisán-Ruiz, Coro;
Guevara, Rocio;
Federoff, Monica;
Hanagasi, Hasmet;
Sina, Fardaz;
Elahi, Elahe;
Schneider, Susanne A.;
Schwingenschuh, Petra;
Bajaj, Nin;
Emre, Murat;
Singleton, Andrew B.;
Hardy, John;
Bhatia, Kailash P.;
Brandner, Sebastian;
Lees, Andrew J.;
Houlden, Henry

Publication type:

Article

Sequencing analysis of the ITPR1 gene in a pure autosomal dominant spinocerebellar ataxia series.

Published in:

Movement Disorders, 2010, v. 25, n. 6, p. 771, doi. 10.1002/mds.22970

By:

van de Leemput, Joyce;
Wavrant-De Vrièze, Fabienne;
Rafferty, Ian;
Bras, Jose M.;
Giunti, Paola;
Fisher, Elizabeth MC;
Hardy, John A.;
Singleton, Andrew B.;
Houlden, Henry

Publication type:

Article

Familial Parkinsonism and early onset Parkinson's disease in a Brazilian movement disorders clinic: Phenotypic characterization and frequency of SNCA, PRKN, PINK1, and LRRK2 mutations.

Published in:

Movement Disorders, 2009, v. 24, n. 5, p. 662, doi. 10.1002/mds.22365

By:

Camargos, Sarah Teixeira;
Dornas, Leonardo Oliveira;
Momeni, Parastoo;
Lees, Andrew;
Hardy, John;
Singleton, Andrew;
Cardoso, Francisco

Publication type:

Article

The TOR1A polymorphism rs1182 and the risk of spread in primary blepharospasm.

Published in:

Movement Disorders, 2009, v. 24, n. 4, p. 613, doi. 10.1002/mds.22471

By:

Defazio, Giovanni;
Matarin, Mar;
Peckham, Elizabeth L.;
Martino, Davide;
Valente, Enza M.;
Singleton, Andrew;
Crawley, Anthony;
Aniello, Maria Stella;
Brancati, Francesco;
Abbruzzese, Giovanni;
Girlanda, Paolo;
Livrea, Paolo;
Hallett, Mark;
Berardelli, Alfredo

Publication type:

Article

Parkin-related disease clinically diagnosed as a pallido-pyramidal syndrome.

Published in:

Movement Disorders, 2009, v. 24, n. 1, p. 138, doi. 10.1002/mds.22181

By:

Wickremaratchi, Mindhu M.;
Majounie, Elisa;
Morris, Huw R.;
Williams, Nigel M.;
Lewis, Helen;
Gill, Steven S.;
Khan, Sadaquate;
Heywood, Peter;
Hardy, John;
Wiles, Charles M.;
Singleton, Andrew B.;
Quinn, Niall P.

Publication type:

Article