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- Title
Picotamide, a combined inhibitor of thromboxane A2 synthase and receptor, reduces 2-year mortality in diabetics with peripheral arterial disease: the DAVID study.
- Authors
Neri Serneri, Gian Gastone; Coccheri, Sergio; Marubini, Ettore; Violi, Francesco; Drug Evaluation in Atherosclerotic Vascular Disease in Diabetics (DAVID) Study Group
- Abstract
Patients with diabetes are at excessive risk of mortality and cardiovascular morbidity. Previous studies suggest that aspirin may be less effective in diabetic patients. In this multi-centre, randomized, double blind trial picotamide, a dual inhibitor of thromboxane A2 synthase and receptor, was compared with aspirin for the prevention of mortality and major cardiovascular events in diabetics with peripheral arterial disease (PAD).
- Publication
European heart journal, 2004, Vol 25, Issue 20, p1845
- ISSN
0195-668X
- Publication type
Journal Article
- DOI
10.1016/j.ehj.2004.07.013