Title

Alcohol metabolism.

Authors

Cederbaum, Arthur I

Abstract

This article describes the pathways and factors that modulate blood alcohol levels and metabolism and describes how the body disposes of alcohol. The various factors that play a role in the distribution of alcohol in the body, influence the absorption of alcohol, and contribute to first-pass metabolism of alcohol are described. Most alcohol is oxidized in the liver, and general principles and overall mechanisms for alcohol oxidation are summarized. The kinetics of alcohol elimination in-vivo and the various genetic and environmental factors that can modify the rate of alcohol metabolism are discussed.

Publication

Clinics in liver disease, 2012, Vol 16, Issue 4, p667

ISSN

1557-8224

Publication type

Journal Article

DOI

10.1016/j.cld.2012.08.002