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- Title
Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice.
- Authors
Marguerie, Anita; Bajolle, Fanny; Zaffran, Stephane; Brown, Nigel A; Dickson, Clive; Buckingham, Margaret E; Kelly, Robert G
- Abstract
Myocardial progenitor cells expressing Fgf10 give rise to the outflow tract and right ventricle of the mammalian heart. In order to define the role of fibroblast growth factor (FGF) signaling in this process we investigated whether Fgf10 or the major Fgf10 receptor Fgfr2-IIIb are required for normal heart development.
- Publication
Cardiovascular research, 2006, Vol 71, Issue 1, p50
- ISSN
0008-6363
- Publication type
Journal Article
- DOI
10.1016/j.cardiores.2006.03.021