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Title
Mechanism of cGMP-mediated protection in a cellular model of myocardial reperfusion injury.
Authors
Abdallah, Y; Gkatzoflia, A; Pieper, H; Zoga, E; Walther, S; Kasseckert, S; Schäfer, M; Schlüter, K D; Piper, H M; Schäfer, C
Abstract
Reperfusion injury of the myocardium is characterised by development of cardiomyocyte hypercontracture. Previous studies have shown that cGMP-mediated stimuli protect against reperfusion injury, but the cellular mechanism is still unknown.