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- Title
Purified cardiomyocytes from bone marrow mesenchymal stem cells produce stable intracardiac grafts in mice.
- Authors
Hattan, Naoichiro; Kawaguchi, Haruko; Ando, Kiyoshi; Kuwabara, Eriko; Fujita, Jun; Murata, Mitsushige; Suematsu, Makoto; Mori, Hidezo; Fukuda, Keiichi
- Abstract
We have previously isolated cardiomyogenic cells from murine bone marrow (CMG cells). Regenerated cardiomyocytes are important candidates for cell transplantation, but as they are stem cell derived, they can be contaminated with various cell types, thereby requiring characterization and purification. Our objectives were to increase the efficiency of cell transplantation and to protect the recipients from possible adverse effects using an efficient and effective purification process as well as to characterize regenerated cardiomyocytes.
- Publication
Cardiovascular research, 2005, Vol 65, Issue 2, p334
- ISSN
0008-6363
- Publication type
Journal Article
- DOI
10.1016/j.cardiores.2004.10.004