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- Title
Comparison of intermediate-term outcomes of coronary artery bypass grafting versus drug-eluting stents for patients ≥75 years of age.
- Authors
Hannan, Edward L; Zhong, Ye; Berger, Peter B; Walford, Gary; Curtis, Jeptha P; Wu, Chuntao; Venditti, Ferdinand J; Higgins, Robert S D; Smith, Craig R; Lahey, Stephen J; King, Spencer B, 3rd
- Abstract
Several randomized controlled trials and observational studies have compared outcomes of percutaneous coronary interventions (PCIs) with drug-eluting stents (DESs) and coronary artery bypass grafting (CABG), but they have not thoroughly investigated the relative difference in outcomes for patients aged ≥75 years. In this study, a total of 3,864 patients receiving DES and CABG (1,932 CABG-DES pairs) with multivessel coronary disease were propensity matched using multiple patient risk factors and were compared with respect to 3 outcomes (mortality, stroke/myocardial infarction [MI]/mortality, and repeat revascularization) at 2.5 years with a mean follow-up of 18 months. The mortality rates (DES/CABG hazard ratio 1.06, 95% confidence interval 0.87 to 1.30) and the stroke/MI/mortality rates (DES/CABG hazard ratio 1.15, 95% confidence interval 0.97 to 1.38) for the 2 procedures were not significantly different. Repeat revascularization rates were significantly higher for patients who received DESs. In conclusion, older patients experienced similar mortality and stroke/MI/mortality rates for CABG and PCI with DES, although repeat revascularization rates were higher for patients undergoing PCI with DES.
- Publication
The American journal of cardiology, 2014, Vol 113, Issue 5, p803
- ISSN
1879-1913
- Publication type
Journal Article
- DOI
10.1016/j.amjcard.2013.11.035