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- Title
Expeditious exclusion of acute coronary syndrome diagnosis by combined measurements of copeptin, high-sensitivity troponin, and GRACE score.
- Authors
Bohyn, Emilie; Dubie, Elophe; Lebrun, Claire; Jund, Jérôme; Beaune, Gaspard; Lesage, Patrick; Belle, Loïc; Savary, Dominique
- Abstract
High-sensitivity troponin (HS-TnT) combined with copeptin have been proposed to expedite the diagnostic exclusion of acute myocardial infarction. The Global Registry of Acute Coronary Events (GRACE) has been validated and recommended by the European Society of Cardiology as a prognostic score in the management of acute coronary syndrome (ACS) without ST-segment elevation (non-ST+) on the electrocardiogram. Our study examined whether a low GRACE score (<108) combined with negative HS-TnT (<14 ng/L) and copeptin (<14 pmol/L) reliably exclude the diagnosis of non-ST+ ACS, including non-ST-segment elevation myocardial infarction and unstable angina.
- Publication
The American journal of emergency medicine, 2014, Vol 32, Issue 4, p293
- ISSN
1532-8171
- Publication type
Journal Article
- DOI
10.1016/j.ajem.2013.11.043