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Title
Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues.
Authors
Blanche, S; Tardieu, M; Rustin, P; Slama, A; Barret, B; Firtion, G; Ciraru-Vigneron, N; Lacroix, C; Rouzioux, C; Mandelbrot, L; Desguerre, I; Rötig, A; Mayaux, M J; Delfraissy, J F
Abstract
Zidovudine is commonly administered during pregnancy to prevent mother-to-child HIV-1 transmission. We investigated mitochondrial toxic effects in children exposed to zidovudine in utero and after birth.