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- Title
Renoprotective properties of ACE-inhibition in non-diabetic nephropathies with non-nephrotic proteinuria.
- Authors
Ruggenenti, P; Perna, A; Gherardi, G; Garini, G; Zoccali, C; Salvadori, M; Scolari, F; Schena, F P; Remuzzi, G
- Abstract
Stratum 2 of the Ramipril Efficacy in Nephropathy (REIN) study has already shown that in patients with chronic nephropathies and proteinuria of 3 g or more per 24 h, angiotensin-converting enzyme (ACE) inhibition reduced the rate of decline in glomerular filtration and halved the combined risk of doubling of serum creatinine or end-stage renal failure (ESRF) found in controls on placebo plus conventional antihypertensives. In REIN stratum 1, reported here, 24 h proteinuria was 1 g or more but less than 3 g per 24 h.
- Publication
Lancet (London, England), 1999, Vol 354, Issue 9176, p359
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(98)10363-X