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- Title
Association of two silent polymorphisms of platelet glycoprotein Ia/IIa receptor with risk of myocardial infarction: a case-control study.
- Authors
Moshfegh, K; Wuillemin, W A; Redondo, M; Lämmle, B; Beer, J H; Liechti-Gallati, S; Meyer, B J
- Abstract
The platelet membrane glycoprotein Ia/IIa plays a major part in platelet function as a primary receptor for collagen. A previous report showed a variation of glycoprotein Ia/IIa receptor density and function associated with two silent and linked polymorphisms (807C/T and 873G/A) within the glycoprotein Ia gene. Because platelet thrombus formation is implicated in the pathogenesis of acute myocardial infarction, we investigated these polymorphisms among patients who had had a myocardial infarction.
- Publication
Lancet (London, England), 1999, Vol 353, Issue 9150, p351
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/s0140-6736(98)06448-4