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- Title
No evidence of pig DNA or retroviral infection in patients with short-term extracorporeal connection to pig kidneys.
- Authors
Patience, C; Patton, G S; Takeuchi, Y; Weiss, R A; McClure, M O; Rydberg, L; Breimer, M E
- Abstract
The xenotransplantation of organs and tissues, in particular those from pigs, is viewed as a means to alleviate the shortage of human donor organs and cells available for transplantation and also as a therapy for other diseases. The potential microbiological hazards of xenotransplantation have recently attracted much attention. One concern is over pig endogenous retroviruses (PERV). Until the possible consequences of infection by PERV are better understood it is unlikely that a significant number of porcine xenotransplants will proceed. However, a small number of patients have already been treated with or exposed to living porcine cells or tissue, and investigation of these patients may provide valuable information.
- Publication
Lancet (London, England), 1998, Vol 352, Issue 9129, p699
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(98)04369-4