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Title
Presence of fetal DNA in maternal plasma and serum.
Authors
Lo, Y M; Corbetta, N; Chamberlain, P F; Rai, V; Sargent, I L; Redman, C W; Wainscoat, J S
Abstract
The potential use of plasma and serum for molecular diagnosis has generated interest. Tumour DNA has been found in 'the plasma and serum of cancer patients, and molecular analysis has been done on this material. We investigated the equivalent condition in pregnancy-that is, whether fetal DNA is present in maternal plasma and serum.