We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment.
- Authors
Pérez, V; Gilaberte, I; Faries, D; Alvarez, E; Artigas, F
- Abstract
Major depression affects more than 5% of the population and is a serious health and economic problem. Antidepressants have a slow onset of action and are effective in less than two-thirds of patients. The biochemical effects of selective serotonin reuptake inhibitors may be limited by the negative feedback from serotonin autoreceptors. Pindolol is an antagonist of both serotonin autoreceptors and beta-adrenoceptors. We studied the effect of the addition of pindolol to fluoxetine antidepressant treatment.
- Publication
Lancet (London, England), 1997, Vol 349, Issue 9065, p1594
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(96)08007-5