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- Title
Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial.
- Authors
Chen, Z M; Pan, H C; Chen, Y P; Peto, R; Collins, R; Jiang, L X; Xie, J X; Liu, L S; COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial) collaborative group
- Abstract
Despite previous randomised trials of early beta-blocker therapy in the emergency treatment of myocardial infarction (MI), uncertainty has persisted about the value of adding it to current standard interventions (eg, aspirin and fibrinolytic therapy), and the balance of potential benefits and hazards is still unclear in high-risk patients.
- Publication
Lancet (London, England), 2005, Vol 366, Issue 9497, p1622
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(05)67661-1