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- Title
Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study.
- Authors
Van Gaal, Luc F; Rissanen, Aila M; Scheen, André J; Ziegler, Olivier; Rössner, Stephan; RIO-Europe Study Group
- Abstract
In animal models, cannabinoid-1 receptor (CB1) blockade produces a lean phenotype, with resistance to diet-induced obesity and associated dyslipidaemia. We assessed the effect of rimonabant, a selective CB1 blocker, on bodyweight and cardiovascular risk factors in overweight or obese patients.
- Publication
Lancet (London, England), 2005, Vol 365, Issue 9468, p1389
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(05)66374-X