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- Title
Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial.
- Authors
McMurray, John J V; Ostergren, Jan; Swedberg, Karl; Granger, Christopher B; Held, Peter; Michelson, Eric L; Olofsson, Bertil; Yusuf, Salim; Pfeffer, Marc A; CHARM Investigators and Committees
- Abstract
Angiotensin II type 1 receptor blockers have favourable effects on haemodynamic measurements, neurohumoral activity, and left-ventricular remodelling when added to angiotensin-converting-enzyme (ACE) inhibitors in patients with chronic heart failure (CHF). We aimed to find out whether these drugs improve clinical outcome.
- Publication
Lancet (London, England), 2003, Vol 362, Issue 9386, p767
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(03)14283-3