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- Title
Prevention of variceal rebleeding.
- Authors
Bosch, Jaume; García-Pagán, Juan Carlos
- Abstract
Variceal bleeding is the most frequent severe complication of portal hypertension and a leading cause of death and liver transplantation in patients with cirrhosis. Patients surviving a variceal bleed are at high risk of rebleeding (over 60% at 1 year). Portacaval shunts and transjugular intrahepatic portasystemic shunts (TIPS) are effective for prevention of rebleeding but carry a high risk of hepatic encephalopathy. Endoscopic techniques include band ligation (EBL) and injection sclerotherapy (EIS). Drug approaches are based on non-selective beta blocker with or without isosorbide-5-mononitrate (ISMN).
- Publication
Lancet (London, England), 2003, Vol 361, Issue 9361, p952
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(03)12778-X