We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Merkel cell carcinoma and HIV infection.
- Authors
Engels, Eric A; Frisch, Morten; Goedert, James J; Biggar, Robert J; Miller, Robert W
- Abstract
Merkel cell carcinoma (MCC) is a rare skin cancer that occurs more frequently after organ transplantation or B-cell malignancy, conditions of suppressed or disordered immunity. To assess further whether immune suppression increases MCC risk, we studied its occurrence in a cohort of 309365 individuals with acquired immunodeficiency syndrome (AIDS) by using linked AIDS and cancer registries. We identified six cases of MCC, corresponding to a relative risk of 13.4 (95% CI 4.9-29.1) compared with the general population. These results suggest that immune suppression induced by the human immunodeficiency virus increases MCC risk.
- Publication
Lancet (London, England), 2002, Vol 359, Issue 9305, p497
- ISSN
0140-6736
- Publication type
Research
- DOI
10.1016/S0140-6736(02)07668-7