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- Title
Long-term effect of bone-marrow transplantation for childhood-onset cerebral X-linked adrenoleukodystrophy.
- Authors
Shapiro, E; Krivit, W; Lockman, L; Jambaqué, I; Peters, C; Cowan, M; Harris, R; Blanche, S; Bordigoni, P; Loes, D; Ziegler, R; Crittenden, M; Ris, D; Berg, B; Cox, C; Moser, H; Fischer, A; Aubourg, P
- Abstract
The childhood-onset cerebral form of X-linked adrenoleukodystrophy, a demyelinating disorder of the central nervous system, leads to a vegetative state and death within 3-5 years once clinical symptoms are detectable. The hypothesis to be tested was whether bone-marrow transplantation can over an extended period of time halt the inexorable progressive demyelination and neurological deterioration.
- Publication
Lancet (London, England), 2000, Vol 356, Issue 9231, p713
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(00)02629-5