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- Title
Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage.
- Authors
Maccarrone, M; Valensise, H; Bari, M; Lazzarin, N; Romanini, C; Finazzi-Agrò, A
- Abstract
Endocannabinoids such as anandamide are thought to have adverse effects on pregnancy and embryonic development. The activity of the degradative enzyme anandamide hydrolase may therefore be crucial for prevention of excessive concentrations of anandamide in the uterus, and thus prevention of pregnancy failure or female infertility. We tested this hypothesis in a preliminary study, and then used the results to find out whether anandamide hydrolase activity could predict miscarriage in a group of pregnant women.
- Publication
Lancet (London, England), 2000, Vol 355, Issue 9212, p1326
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(00)02115-2