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- Title
Cysticercosis as a major cause of epilepsy in Peru. The Cysticercosis Working Group in Peru (CWG)
- Authors
Garcia, H H; Gilman, R; Martinez, M; Tsang, V C; Pilcher, J B; Herrera, G; Diaz, F; Alvarado, M; Miranda, E
- Abstract
In countries where cysticercosis is endemic, the proportion of epilepsy due to cysticercosis is not well documented. To investigate the association between cysticercosis and epilepsy, we used the enzyme-linked immunoelectrotransfer blot (EITB) assay to detect serum antibodies to Taenia solium in 498 consecutive outpatients at a neurology clinic in Lima, Peru. Every patient was classified as epileptic (n = 189) or non-epileptic (n = 309) after neurological, and where possible electroencephalographic, examination. A substantially higher proportion of epileptic than non-epileptic patients was seropositive in the EITB (22 [12%] vs 8 [3%], p < 0.001). 19% of epileptic patients born outside Lima, 20% of those with late-onset epilepsy, and 29% of patients with both these characteristics were seropositive. Thus, in Peru, cysticercosis is an important aetiological factor for epilepsy.
- Publication
Lancet (London, England), 1993, Vol 341, Issue 8839, p197
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/0140-6736(93)90064-n