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- Title
Population pharmacokinetics of tobramycin in patients with and without cystic fibrosis.
- Authors
Hennig, Stefanie; Standing, Joseph F; Staatz, Christine E; Thomson, Alison H
- Abstract
While several studies have examined the pharmacokinetics of tobramycin in patients with cystic fibrosis (CF), there is no consensus on whether they differ in patients with and without CF. The objectives of this study were to identify covariates which explain pharmacokinetic variability and to examine whether having the disease CF in itself alters these relationships and drug dose requirements.
- Publication
Clinical pharmacokinetics, 2013, Vol 52, Issue 4, p289
- ISSN
1179-1926
- Publication type
Journal Article
- DOI
10.1007/s40262-013-0036-y