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- Title
FOXP3 expression and nodal metastasis of breast cancer.
- Authors
Gökmen-Polar, Yesim; Thorat, Mangesh A; Sojitra, Payal; Saxena, Rashmil; Badve, Sunil
- Abstract
T regulatory cells, a subset of T lymphocytes, function to suppress immune responses. FOXP3, a member of the forkhead family of transcription factors, is a good marker for T regulatory cells. Since sentinel nodes are important sites of immunomodulation in breast cancer, we studied the association between T regulatory cells and nodal metastasis using FOXP3 expression in sentinel nodes with and without metastatic breast carcinoma.
- Publication
Cellular oncology (Dordrecht), 2013, Vol 36, Issue 5, p405
- ISSN
2211-3436
- Publication type
Journal Article
- DOI
10.1007/s13402-013-0147-3