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- Title
In vitro treatment of carcinoma cell lines with pancreatic (pro)enzymes suppresses the EMT programme and promotes cell differentiation.
- Authors
Perán, Macarena; Marchal, Juan Antonio; García, Maria A; Kenyon, Julian; Tosh, David
- Abstract
Previous research has suggested a putative utility of pancreatic (pro)enzymes in cancer treatment. The aim of the present study was to investigate the in vitro effects of a mixture of two pancreatic pro-enzymes, i.e., Chymotrypsinogen and Trypsinogen, and the enzyme Amylase on three human cancer cell lines, i.e., OE33 (derived from an oesophageal carcinoma), Panc1 (derived from a pancreatic carcinoma) and Caco-2 (derived from a colon carcinoma).
- Publication
Cellular oncology (Dordrecht), 2013, Vol 36, Issue 4, p289
- ISSN
2211-3436
- Publication type
Journal Article
- DOI
10.1007/s13402-013-0134-8