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- Title
Overexpression of a splice variant of oncostatin M receptor beta in human esophageal squamous carcinoma.
- Authors
Kausar, Tasneem; Sharma, Rinu; Hasan, Md Raghibul; Saraya, Anoop; Chattopadhyay, Tushar K; Gupta, Siddartha Datta; Ralhan, Ranju
- Abstract
Expression of oncostatin M receptor beta (OSMRβ) has been reported in human cancers, however its role in esophageal squamous cell carcinoma (ESCC) remains unknown. Using differential display, earlier we reported the identification of an alternatively spliced variant of OSMRβ in ESCC. Here in we characterized this novel variant encoding a soluble form of this receptor (sOSMRβ) and determined its clinical significance and correlation with the expression of oncostatin (OSM) and leukemia inhibitory factor receptor beta (LIFR β) in ESCC.
- Publication
Cellular oncology (Dordrecht), 2011, Vol 34, Issue 3, p177
- ISSN
2211-3436
- Publication type
Journal Article
- DOI
10.1007/s13402-011-0011-2