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Title
Are dosing adjustments required for colchicine in the elderly compared with younger patients?
Authors
Wason, Suman; Faulkner, Robert D; Davis, Matthew W
Abstract
The objective of this study was to compare the relative bioavailability of the US Food and Drug Administration-approved formulation of colchicine after a single 0.6 mg dose in young (18-30 years of age) and elderly (≥60 years of age) healthy subjects to determine whether dosing adjustments are required in elderly patients.