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- Title
Translocation t(6;14) as the sole chromosomal abnormality in adenoid cystic carcinoma of the base of tongue.
- Authors
Bell, Diana; Zhao, Yi-Jue; Rao, Pulivarthi H; Weber, Randal S; El-Naggar, Adel K
- Abstract
We present an adenoid cystic carcinoma of the base of tongue in a 48-year-old male with a restricted chromosomal alteration by cytogenetic and spectral karyotypic analysis (SKY). SKY and G-banding analyses identified the t(6;14)(q25;q13) as the sole structural aberration in all metaphases analyzed. This finding supports a critical role for this event in the development of this tumor. The implications of chromosome 6q translocation in this case and in previously reported adenoid cystic carcinomas are highlighted and discussed.
- Publication
Head and neck pathology, 2007, Vol 1, Issue 2, p165
- ISSN
1936-0568
- Publication type
Journal Article
- DOI
10.1007/s12105-007-0030-5