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- Title
A rare case of metastatic pancreatic hepatoid carcinoma treated with sorafenib.
- Authors
Petrelli, Fausto; Ghilardi, Maria; Colombo, Silvia; Stringhi, Enrico; Barbara, Cecilia; Cabiddu, Mary; Elia, Stefano; Corti, Daniela; Barni, Sandro
- Abstract
Hepatoid carcinoma (HC) is a rare histopathological tumor type with prominent features of hepatoid differentiation, and while most of the reported cases are of gastric origin, ten cases of pancreatic HC have been reported to date. The majority of HC cases are metastatic at presentation, mainly to the liver, lymph nodes, and lungs. They are aggressive, invading, and proliferating in the venous and lymphatic systems, with a behavior similar to that of hepatocellular carcinoma. Diagnosis is challenging: alpha-Fetoprotein, the most useful marker, is not always positive.
- Publication
Journal of gastrointestinal cancer, 2012, Vol 43, Issue 1, p97
- ISSN
1941-6636
- Publication type
Journal Article
- DOI
10.1007/s12029-011-9264-2