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- Title
A 67-year-old woman with BRCA 1 mutation associated with pancreatic adenocarcinoma.
- Authors
Lowery, Maeve; Shah, Manish A; Smyth, Elizabeth; Epstein, Andrew; Segal, Amiel; Rosengarten, Ora; Isacson, Rut; Drukker, Lior; Keinan, Anner; Rachkiman, Meir; Reissman, Petachae; Gabizon, Alberto; Kelsen, David; O'Reilly, Eileen M
- Abstract
There are approximately 40,000 new cases of pancreatic adenocarcinoma diagnosed in the USA each year. It is estimated that 5-10% of all patients with pancreatic cancer have a first-degree relative with the disease, while up to 20% of cases have a hereditary component. Individuals who carry a germline mutation in the BRCA 1 or 2 genes have an increased lifetime risk of developing pancreatic adenocarcinoma when compared with the general population.
- Publication
Journal of gastrointestinal cancer, 2011, Vol 42, Issue 3, p160
- ISSN
1941-6636
- Publication type
Journal Article
- DOI
10.1007/s12029-010-9197-1