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- Title
Downstaging of hepatocellular carcinoma prior to liver transplant: is there a role for adjuvant sorafenib in locoregional therapy?
- Authors
Vagefi, Parsia A; Hirose, Ryutaro
- Abstract
Hepatocellular carcinoma (HCC) remains a common cause of mortality worldwide. Liver transplantation has emerged as the optimal treatment for cirrhotic patients with HCC; however, the shortage of donor organs leaves waitlisted patients at risk for disease progression beyond transplant criteria. Prevention of waitlist dropout has fueled investigation into a wide array of locoregional therapies for the management of HCC in candidates awaiting liver transplantation. We present a patient with HCC who underwent treatment with sorafenib, which resulted in a remarkable reduction in tumor burden to allow for liver transplant listing.
- Publication
Journal of gastrointestinal cancer, 2010, Vol 41, Issue 4, p217
- ISSN
1941-6636
- Publication type
Journal Article
- DOI
10.1007/s12029-010-9163-y