Your institution may have access to this item. Find your institution then sign in to continue.
Title
The tumor suppressor function of human sulfatase 1 (SULF1) in carcinogenesis.
Authors
Lai, Jin-Ping; Sandhu, Dalbir S; Shire, Abdirashid M; Roberts, Lewis R
Abstract
Human sulfatase 1 (SULF1) was recently identified and shown to desulfate cellular heparan sulfate proteoglycans (HSPGs). Since sulfated HSPGs serve as co-receptors for many growth factors and cytokines, SULF1 was predicted to modulate growth factor and cytokine signaling.
Publication
Journal of gastrointestinal cancer, 2008, Vol 39, Issue 1-4, p149